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Degradation-Suppressed Cocoonase for Investigating the Propeptide-Mediated Activation Mechanism

Cocoonase is folded in the form of a zymogen precursor protein (prococoonase) with the assistance of the propeptide region. To investigate the role of the propeptide sequence on the disulfide-coupled folding of cocoonase and prococoonase, the amino acid residues at the degradation sites during the r...

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Detalles Bibliográficos
Autores principales: Sakata, Nana, Ogata, Ayumi, Takegawa, Mai, Murakami, Yuri, Nishimura, Misaki, Miyazawa, Mitsuhiro, Hagiwara, Teruki, Shimamoto, Shigeru, Hidaka, Yuji
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693254/
https://www.ncbi.nlm.nih.gov/pubmed/36432163
http://dx.doi.org/10.3390/molecules27228063