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Pharmacogenetics Role of Genetic Variants in Immune-Related Factors: A Systematic Review Focusing on mCRC

Pharmacogenetics plays a key role in personalized cancer treatment. Currently, the clinically available pharmacogenetic markers for metastatic colorectal cancer (mCRC) are in genes related to drug metabolism, such as DPYD for fluoropyrimidines and UGT1A1 for irinotecan. Recently, the impact of host...

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Detalles Bibliográficos
Autores principales: Scarabel, Lucia, Bignucolo, Alessia, Toffoli, Giuseppe, Cecchin, Erika, De Mattia, Elena
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693433/
https://www.ncbi.nlm.nih.gov/pubmed/36432658
http://dx.doi.org/10.3390/pharmaceutics14112468