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Compression Density as an Alternative to Identify an Optimal Moisture Content for High Shear Wet Granulation as an Initial Step for Spheronisation

Pellet production is a multi-step manufacturing process comprising granulation, extrusion and spheronisation. The first step represents a critical control point, since the quality of the granule mass highly influences subsequent process steps and, consequently, the quality of final pellets. The most...

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Detalles Bibliográficos
Autores principales: Ramm, Selina, Fulek, Ruwen, Eberle, Veronika Anna, Kiera, Christian, Odefey, Ulrich, Pein-Hackelbusch, Miriam
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693446/
https://www.ncbi.nlm.nih.gov/pubmed/36365122
http://dx.doi.org/10.3390/pharmaceutics14112303