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Pharmacogenetic Study of the Impact of ABCB1 Single Nucleotide Polymorphisms on the Response to Cyclosporine in Psoriasis Patients

Psoriasis is a chronic, T cell-mediated skin disease affecting 2–3% of the Caucasian population. Cyclosporine A is a calcineurin inhibitor that acts selectively on T cells. The cyclosporine A treatment response has been suggested to be modulated by single-nucleotide polymorphisms (SNPs) in the ABCB1...

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Detalles Bibliográficos
Autores principales: Chernov, Alexandr, Kilina, Daria, Smirnova, Tatiana, Galimova, Elvira
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693450/
https://www.ncbi.nlm.nih.gov/pubmed/36432633
http://dx.doi.org/10.3390/pharmaceutics14112441