Synthesis of Tetrasubstituted Phosphorus Analogs of Aspartic Acid as Antiproliferative Agents

An efficient general method for the synthesis of a wide family of α-aminophosphonate analogs of aspartic acid bearing tetrasubstituted carbons is reported through an aza-Reformatsky reaction of α-iminophosphonates, generated from α-aminophosphonates, in an umpolung process. In addition, the α-aminop...

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Detalles Bibliográficos
Autores principales: del Corte, Xabier, Maestro, Aitor, López-Francés, Adrián, Palacios, Francisco, Vicario, Javier
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693455/
https://www.ncbi.nlm.nih.gov/pubmed/36432120
http://dx.doi.org/10.3390/molecules27228024

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693455/
https://www.ncbi.nlm.nih.gov/pubmed/36432120
http://dx.doi.org/10.3390/molecules27228024

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