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Synthesis of Tetrasubstituted Phosphorus Analogs of Aspartic Acid as Antiproliferative Agents

An efficient general method for the synthesis of a wide family of α-aminophosphonate analogs of aspartic acid bearing tetrasubstituted carbons is reported through an aza-Reformatsky reaction of α-iminophosphonates, generated from α-aminophosphonates, in an umpolung process. In addition, the α-aminop...

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Detalles Bibliográficos
Autores principales:	del Corte, Xabier, Maestro, Aitor, López-Francés, Adrián, Palacios, Francisco, Vicario, Javier
Formato:	Online Artículo Texto
Lenguaje:	English
Publicado:	MDPI 2022
Materias:	Article
Acceso en línea:	https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693455/ https://www.ncbi.nlm.nih.gov/pubmed/36432120 http://dx.doi.org/10.3390/molecules27228024

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