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Old and New Facts and Speculations on the Role of the B Cell Receptor in the Origin of Chronic Lymphocytic Leukemia

The engagement of the B cell receptor (BcR) on the surface of leukemic cells represents a key event in chronic lymphocytic leukemia (CLL) since it can lead to the maintenance and expansion of the neoplastic clone. This notion was initially suggested by observations of the CLL BcR repertoire and of c...

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Detalles Bibliográficos
Autores principales: Bagnara, Davide, Mazzarello, Andrea Nicola, Ghiotto, Fabio, Colombo, Monica, Cutrona, Giovanna, Fais, Franco, Ferrarini, Manlio
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693457/
https://www.ncbi.nlm.nih.gov/pubmed/36430731
http://dx.doi.org/10.3390/ijms232214249