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Fasudil Ameliorates Methotrexate-Induced Hepatotoxicity by Modulation of Redox-Sensitive Signals

Methotrexate (MTX) is one of the most widely used cytotoxic chemotherapeutic agents, and it is used in the treatment of different autoimmune disorders. However, the clinical applications of MTX are limited by its hepatic toxicity. Hence, the present study was conducted to evaluate the efficacy of fa...

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Detalles Bibliográficos
Autores principales: Aboubakr, Esam M., Ibrahim, Ahmed R. N., Ali, Fares E. M., Mourad, Ahmed A. E., Ahmad, Adel M., Hofni, Amal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693476/
https://www.ncbi.nlm.nih.gov/pubmed/36422565
http://dx.doi.org/10.3390/ph15111436