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IL-17/Notch1/STAT3 Pathway Contributes to 5-Fluorouracil-Induced Intestinal Mucositis in Rats: Amelioration by Thymol Treatment

5-Fluorouracil (5-FU) is an anticancer drug with intestinal mucositis (IM) as a deleterious side effect. Thymol is a monoterpene phenol which has been reported to possess an antioxidant and anti-inflammatory activity versus 5-FU-induced IM. The Notch pathway affects multiple cellular activities, suc...

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Detalles Bibliográficos
Autores principales: Badr, Amira M., Alkharashi, Layla A., Sherif, Iman O., Alanteet, Alaa A., Alotaibi, Hind N., Mahran, Yasmen F.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693479/
https://www.ncbi.nlm.nih.gov/pubmed/36422542
http://dx.doi.org/10.3390/ph15111412