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Targeting Multiple Homeostasis-Maintaining Systems by Ionophore Nigericin Is a Novel Approach for Senolysis

Within the present study we proposed a novel approach for senolysis based on the simultaneous disturbance of the several homeostasis-maintaining systems in senescent cells including intracellular ionic balance, energy production and intracellular utilization of damaged products. Of note, we could no...

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Detalles Bibliográficos
Autores principales: Deryabin, Pavel I., Shatrova, Alla N., Borodkina, Aleksandra V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693507/
https://www.ncbi.nlm.nih.gov/pubmed/36430735
http://dx.doi.org/10.3390/ijms232214251