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Activation of Interferon-Stimulated Genes following Varicella-Zoster Virus Infection in a Human iPSC-Derived Neuronal In Vitro Model Depends on Exogenous Interferon-α

Varicella-zoster virus (VZV) infection of neuronal cells and the activation of cell-intrinsic antiviral responses upon infection are still poorly understood mainly due to the scarcity of suitable human in vitro models that are available to study VZV. We developed a compartmentalized human-induced pl...

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Detalles Bibliográficos
Autores principales: Boeren, Marlies, Van Breedam, Elise, Buyle-Huybrecht, Tamariche, Lebrun, Marielle, Meysman, Pieter, Sadzot-Delvaux, Catherine, Van Tendeloo, Viggo F., Mortier, Geert, Laukens, Kris, Ogunjimi, Benson, Ponsaerts, Peter, Delputte, Peter
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693540/
https://www.ncbi.nlm.nih.gov/pubmed/36423126
http://dx.doi.org/10.3390/v14112517