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Human Umbilical Cord MSC Delivered-Soluble TRAIL Inhibits the Proliferation and Promotes Apoptosis of B-ALL Cell In Vitro and In Vivo

The TNF-related apoptosis-inducing ligand (TRAIL) could induce apoptosis of leukemic cells, while showed no cytotoxic effect on normal cells. One of the limitations for application of recombinant TRAIL (rhTRAIL) in leukemia treatment is that the serum half-life of this protein is short. Gene deliver...

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Detalles Bibliográficos
Autores principales: Chen, Fangshan, Zhong, Xianmei, Dai, Qian, Li, Kuo, Zhang, Wei, Wang, Jie, Zhao, Yueshui, Shen, Jing, Xiao, Zhangang, Xing, Hongyun, Li, Jing
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693801/
https://www.ncbi.nlm.nih.gov/pubmed/36422522
http://dx.doi.org/10.3390/ph15111391