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Non-Viral Gene Therapy in Trabecular Meshwork Cells to Prevent Fibrosis in Minimally Invasive Glaucoma Surgery

The primary cause of failure for minimally invasive glaucoma surgery (MIGS) is fibrosis in the trabecular meshwork (TM) that regulates the outflow of aqueous humour, and no anti-fibrotic drug is available for intraocular use in MIGS. The myocardin-related transcription factor/serum response factor (...

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Detalles Bibliográficos
Autores principales: Luo, Jinyuan, Tan, Greymi, Thong, Kai Xin, Kafetzis, Konstantinos N., Vallabh, Neeru, Sheridan, Carl M., Sato, Yusuke, Harashima, Hideyoshi, Tagalakis, Aristides D., Yu-Wai-Man, Cynthia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693853/
https://www.ncbi.nlm.nih.gov/pubmed/36432663
http://dx.doi.org/10.3390/pharmaceutics14112472