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Concomitant Administration of Capecitabine and Folate Supplements: Need to Encourage Medication Reconciliation

Hand-Foot syndrome (HFS) and diarrhoea are dose-limiting Adverse Drug Reactions (ADRs) of capecitabine-based chemotherapy. Four polymorphisms in the dihydropyrimidine dehydrogenase (DPYD) gene, encoding the DPD enzyme responsible for the metabolism of fluoropyrimidines, such as capecitabine, are str...

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Detalles Bibliográficos
Autores principales: Stefanelli, Berenice, Sellitto, Carmine, De Bellis, Emanuela, Torsiello, Martina, Bertini, Nicola, Pezzullo, Angelo Maria, Corbi, Graziamaria, Sabbatino, Francesco, Pepe, Stefano, Tesse, Angela, Conti, Valeria, Filippelli, Amelia
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9693983/
https://www.ncbi.nlm.nih.gov/pubmed/36355560
http://dx.doi.org/10.3390/ph15111388