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Structural Basis for (2R,3R)-Taxifolin Binding and Reaction Products to the Bacterial Chalcone Isomerase of Eubacterium ramulus

The bacterial chalcone isomerase (CHI) from Eubacterium ramulus catalyses the first step in a flavanone-degradation pathway by a reverse Michael addition. The overall fold and the constitution of the active site of the enzyme completely differ from the well-characterised chalcone isomerase of plants...

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Detalles Bibliográficos
Autores principales: Palm, Gottfried J., Thomsen, Maren, Berndt, Leona, Hinrichs, Winfried
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694015/
https://www.ncbi.nlm.nih.gov/pubmed/36432010
http://dx.doi.org/10.3390/molecules27227909