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Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress

Tripterygium glycoside tablet (TGT), as a common clinical drug, can easily cause liver damage due to the narrow therapeutic window. Glycyrrhizic acid (GA) has a hepatoprotective effect, but the characteristics and mechanism of GA’s impact on TGT-induced acute liver injury by regulating oxidative str...

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Detalles Bibliográficos
Autores principales: Wang, Qixin, Huang, Yuwen, Li, Yu, Zhang, Luyun, Tang, Huan, Zhang, Junzhe, Cheng, Guangqing, Zhao, Minghong, Lu, Tianming, Zhang, Qian, Luo, Piao, Zhu, Yinhua, Xia, Fei, Zhang, Ying, Liu, Dandan, Wang, Chen, Li, Haiyan, Qiu, Chong, Wang, Jigang, Guo, Qiuyan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694034/
https://www.ncbi.nlm.nih.gov/pubmed/36422270
http://dx.doi.org/10.3390/metabo12111128