Cargando…
Glycyrrhizic Acid Mitigates Tripterygium-Glycoside-Tablet-Induced Acute Liver Injury via PKM2 Regulated Oxidative Stress
Tripterygium glycoside tablet (TGT), as a common clinical drug, can easily cause liver damage due to the narrow therapeutic window. Glycyrrhizic acid (GA) has a hepatoprotective effect, but the characteristics and mechanism of GA’s impact on TGT-induced acute liver injury by regulating oxidative str...
Autores principales: | Wang, Qixin, Huang, Yuwen, Li, Yu, Zhang, Luyun, Tang, Huan, Zhang, Junzhe, Cheng, Guangqing, Zhao, Minghong, Lu, Tianming, Zhang, Qian, Luo, Piao, Zhu, Yinhua, Xia, Fei, Zhang, Ying, Liu, Dandan, Wang, Chen, Li, Haiyan, Qiu, Chong, Wang, Jigang, Guo, Qiuyan |
---|---|
Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
|
Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694034/ https://www.ncbi.nlm.nih.gov/pubmed/36422270 http://dx.doi.org/10.3390/metabo12111128 |
Ejemplares similares
-
Single-cell transcriptome analysis uncovers underlying mechanisms of acute liver injury induced by tripterygium glycosides tablet in mice
por: Guo, Qiuyan, et al.
Publicado: (2023) -
Transcriptome and Lipid Metabolomics-Based Discovery: Glycyrrhizic Acid Alleviates Tripterygium Glycoside Tablet-Induced Acute Liver Injury by Regulating the Activities of CYP and the Metabolism of Phosphoglycerides
por: Shi, Qiaoli, et al.
Publicado: (2022) -
Glycyrrhizic acid glycosides reduces extensive tripterygium glycosides-induced lipid deposition in hepatocytes
por: Yang, Yifei, et al.
Publicado: (2023) -
Clinical Practice Guideline for Tripterygium Glycosides/Tripterygium wilfordii Tablets in the Treatment of Rheumatoid Arthritis
por: Lin, Na, et al.
Publicado: (2021) -
Tripterygium wilfordii glycosides ameliorates collagen-induced arthritis and aberrant lipid metabolism in rats
por: Zhu, Yitian, et al.
Publicado: (2022)