Cargando…

Stress response protein REDD1 promotes diabetes-induced retinal inflammation by sustaining canonical NF-κB signaling

Inflammation contributes to the progression of retinal pathology caused by diabetes. Here, we investigated a role for the stress response protein regulated in development and DNA damage response 1 (REDD1) in the development of retinal inflammation. Increased REDD1 expression was observed in the reti...

Descripción completa

Detalles Bibliográficos
Autores principales: Sunilkumar, Siddharth, Toro, Allyson L., McCurry, Christopher M., VanCleave, Ashley M., Stevens, Shaunaci A., Miller, William P., Kimball, Scot R., Dennis, Michael D.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: American Society for Biochemistry and Molecular Biology 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694114/
https://www.ncbi.nlm.nih.gov/pubmed/36309088
http://dx.doi.org/10.1016/j.jbc.2022.102638