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Neurodegenerative Diseases: From Dysproteostasis, Altered Calcium Signalosome to Selective Neuronal Vulnerability to AAV-Mediated Gene Therapy

Despite intense research into the multifaceted etiology of neurodegenerative diseases (ND), they remain incurable. Here we provide a brief overview of several major ND and explore novel therapeutic approaches. Although the cause (s) of ND are not fully understood, the accumulation of misfolded/aggre...

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Detalles Bibliográficos
Autores principales: Quach, Tam T., Stratton, Harrison J., Khanna, Rajesh, Mackey-Alfonso, Sabrina, Deems, Nicolas, Honnorat, Jérome, Meyer, Kathrin, Duchemin, Anne-Marie
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694178/
https://www.ncbi.nlm.nih.gov/pubmed/36430666
http://dx.doi.org/10.3390/ijms232214188