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An In-Silico Identification of Potential Flavonoids against Kidney Fibrosis Targeting TGFβR-1

Fibrosis is a hallmark of progressive kidney diseases. The overexpression of profibrotic cytokine, namely transforming growth factor β (TGF-β) due to excessive inflammation and tissue damage, induces kidney fibrosis. The inhibition of TGF-β signaling is markedly limited in experimental disease model...

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Detalles Bibliográficos
Autores principales: Rahman, MD. Hasanur, Biswas, Partha, Dey, Dipta, Hannan, Md. Abdul, Sahabuddin, Md., Araf, Yusha, Kwon, Youngjoo, Emran, Talha Bin, Ali, Md. Sarafat, Uddin, Md Jamal
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694304/
https://www.ncbi.nlm.nih.gov/pubmed/36362919
http://dx.doi.org/10.3390/life12111764