Synthesis and Biological Evaluation of a Fused Structure of Indolizine and Pyrrolo[1,2-c]pyrimidine: Identification of Its Potent Anticancer Activity against Liver Cancer Cells

A highly efficient approach to a new indolizine scaffold fused with pyrrolo[1,2-c]pyrimidine was achieved via one-pot three-component coupling followed by an oxidative cyclization reaction. The simple two-step sequence allowed rapid access to various tetracyclic compounds from commercially available...

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Detalles Bibliográficos
Autores principales: Nam, Seonghyeon, Lee, Yechan, Park, So-Hyeon, Namkung, Wan, Kim, Ikyon
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694334/
https://www.ncbi.nlm.nih.gov/pubmed/36422525
http://dx.doi.org/10.3390/ph15111395

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694334/
https://www.ncbi.nlm.nih.gov/pubmed/36422525
http://dx.doi.org/10.3390/ph15111395

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