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Red Blood Cell Membrane Cholesterol May Be a Key Regulator of Sickle Cell Disease Microvascular Complications

Cell membrane lipid composition, especially cholesterol, affects many functions of embedded enzymes, transporters and receptors in red blood cells (RBC). High membrane cholesterol content affects the RBCs’ main vital function, O(2) and CO(2) transport and delivery, with consequences on peripheral ti...

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Detalles Bibliográficos
Autores principales: Niesor, Eric J., Nader, Elie, Perez, Anne, Lamour, François, Benghozi, Renée, Remaley, Alan, Thein, Swee Lay, Connes, Philippe
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694375/
https://www.ncbi.nlm.nih.gov/pubmed/36422126
http://dx.doi.org/10.3390/membranes12111134