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Red Blood Cell Membrane Cholesterol May Be a Key Regulator of Sickle Cell Disease Microvascular Complications
Cell membrane lipid composition, especially cholesterol, affects many functions of embedded enzymes, transporters and receptors in red blood cells (RBC). High membrane cholesterol content affects the RBCs’ main vital function, O(2) and CO(2) transport and delivery, with consequences on peripheral ti...
Autores principales: | Niesor, Eric J., Nader, Elie, Perez, Anne, Lamour, François, Benghozi, Renée, Remaley, Alan, Thein, Swee Lay, Connes, Philippe |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694375/ https://www.ncbi.nlm.nih.gov/pubmed/36422126 http://dx.doi.org/10.3390/membranes12111134 |
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