Covalent Warheads Targeting Cysteine Residue: The Promising Approach in Drug Development

Cysteine is one of the least abundant amino acids in proteins of many organisms, which plays a crucial role in catalysis, signal transduction, and redox regulation of gene expression. The thiol group of cysteine possesses the ability to perform nucleophilic and redox-active functions that are not fe...

Descripción completa

Detalles Bibliográficos
Autores principales: Huang, Fangjiao, Han, Xiaoli, Xiao, Xiaohui, Zhou, Jinming
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694382/
https://www.ncbi.nlm.nih.gov/pubmed/36431829
http://dx.doi.org/10.3390/molecules27227728

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694382/
https://www.ncbi.nlm.nih.gov/pubmed/36431829
http://dx.doi.org/10.3390/molecules27227728

Ejemplares similares