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Covalent Warheads Targeting Cysteine Residue: The Promising Approach in Drug Development
Cysteine is one of the least abundant amino acids in proteins of many organisms, which plays a crucial role in catalysis, signal transduction, and redox regulation of gene expression. The thiol group of cysteine possesses the ability to perform nucleophilic and redox-active functions that are not fe...
| Autores principales: | , , , |
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| Formato: | Online Artículo Texto |
| Lenguaje: | English |
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MDPI
2022
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| Materias: | |
| Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694382/ https://www.ncbi.nlm.nih.gov/pubmed/36431829 http://dx.doi.org/10.3390/molecules27227728 |