A Polymorphism in the Gene Encoding Heat Shock Factor 1 (HSF1) Increases the Risk of Type 2 Diabetes: A Pilot Study Supports a Role for Impaired Protein Folding in Disease Pathogenesis

The aim of this pilot study was to investigate whether polymorphisms in the gene encoding heat shock factor 1 (HSF1), a transcriptional activator of molecular chaperones, play a role in the development of type 2 diabetes (T2D). A total of 3229 unrelated individuals of Slavic origin, including 1569 T...

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Detalles Bibliográficos
Autores principales: Klyosova, Elena, Azarova, Iuliia, Polonikov, Alexey
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694443/
https://www.ncbi.nlm.nih.gov/pubmed/36431071
http://dx.doi.org/10.3390/life12111936

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694443/
https://www.ncbi.nlm.nih.gov/pubmed/36431071
http://dx.doi.org/10.3390/life12111936

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