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Synthesis of Paclitaxel Derivatives for Remote Loading into Liposomes and Improved Therapeutic Effect
A series of novel paclitaxel derivatives modified by boronic acid according to the characteristics of the interaction between RB(OH)(2) and different strapping agents of intraliposomal aqueous phase were designed and synthesized, which were then used to develop remote poorly water-soluble drugs load...
Autores principales: | , , , , , , , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694711/ https://www.ncbi.nlm.nih.gov/pubmed/36432067 http://dx.doi.org/10.3390/molecules27227967 |