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Synthesis of Paclitaxel Derivatives for Remote Loading into Liposomes and Improved Therapeutic Effect

A series of novel paclitaxel derivatives modified by boronic acid according to the characteristics of the interaction between RB(OH)(2) and different strapping agents of intraliposomal aqueous phase were designed and synthesized, which were then used to develop remote poorly water-soluble drugs load...

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Detalles Bibliográficos
Autores principales: Xu, Xiangwei, Liu, Yanhua, Shao, Shanshan, Li, Jinbo, Xu, Zhaochu, Yin, Yueling, Zhao, Linxiang, Wang, Yongjun, Liu, Dan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694711/
https://www.ncbi.nlm.nih.gov/pubmed/36432067
http://dx.doi.org/10.3390/molecules27227967