Investigation of Genetic Variants Associated with Tryptophan Metabolite Levels via Serotonin and Kynurenine Pathways in Patients with Bipolar Disorder

The kynurenine pathway (KP) may play a role in the pathophysiology of bipolar disorder (BD). We conducted a genome-wide association study (GWAS) to identify genetic variants associated with the plasma levels of the metabolites of tryptophan (TRP) via the serotonin (5-HT) and kynurenine (KYN) pathway...

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Detalles Bibliográficos
Autores principales: Pisanu, Claudia, Squassina, Alessio, Paribello, Pasquale, Dall’Acqua, Stefano, Sut, Stefania, Nasini, Sofia, Bertazzo, Antonella, Congiu, Donatella, Meloni, Anna, Garzilli, Mario, Guiso, Beatrice, Suprani, Federico, Pulcinelli, Vittoria, Iaselli, Maria Novella, Pinna, Ilaria, Somaini, Giulia, Arru, Laura, Corrias, Carolina, Pinna, Federica, Carpiniello, Bernardo, Comai, Stefano, Manchia, Mirko
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694761/
https://www.ncbi.nlm.nih.gov/pubmed/36422266
http://dx.doi.org/10.3390/metabo12111127

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694761/
https://www.ncbi.nlm.nih.gov/pubmed/36422266
http://dx.doi.org/10.3390/metabo12111127

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