Insights into the Inhibitory Mechanism of Viniferifuran on Xanthine Oxidase by Multiple Spectroscopic Techniques and Molecular Docking

Viniferifuran was investigated for its potential to inhibit the activity of xanthine oxidase (XO), a key enzyme catalyzing xanthine to uric acid. An enzyme kinetics analysis showed that viniferifuran possessed a strong inhibition on XO in a typical anti-competitive manner with an IC(50) value of 12....

Descripción completa

Detalles Bibliográficos
Autores principales: Yang, Yaxin, Chen, Qian, Ruan, Shiyang, Ao, Junli, Liao, Shang-Gao
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694772/
https://www.ncbi.nlm.nih.gov/pubmed/36431832
http://dx.doi.org/10.3390/molecules27227730

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694772/
https://www.ncbi.nlm.nih.gov/pubmed/36431832
http://dx.doi.org/10.3390/molecules27227730

Ejemplares similares