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In-Vitro, In-Vivo, Molecular Docking and ADMET Studies of 2-Substituted 3,7-Dihydroxy-4H-chromen-4-one for Oxidative Stress, Inflammation and Alzheimer’s Disease

Plants’ bioactives are well-known safe drugs for vital diseases. Flavones and Flavonoid-rich dietary supplements are known to exhibit neuroprotective potential. In this study, we isolated a flavone 2-(3,4-dimethoxyphenyl)-3,7-dihydroxy-4H-chromen-4-one from Notholirion thomsonianum and it was evalua...

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Detalles Bibliográficos
Autores principales: Mahnashi, Mater H., Alshahrani, Mohammed Abdulrahman, Nahari, Mohammed H., Hassan, Syed Shams ul, Jan, Muhammad Saeed, Ayaz, Muhammad, Ullah, Farhat, Alshehri, Osama M., Alshehri, Mohammad Ali, Rashid, Umer, Sadiq, Abdul
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694897/
https://www.ncbi.nlm.nih.gov/pubmed/36355138
http://dx.doi.org/10.3390/metabo12111055