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Revealing the Pathogenesis of Salt-Sensitive Hypertension in Dahl Salt-Sensitive Rats through Integrated Multi-Omics Analysis

Salt-induced renal metabolism dysfunction is an important mechanism of salt-sensitive hypertension. Given that the gut-liver axis is the first hit of a high-salt diet (HSD), we aimed to identify the extra-renal mechanism from hepatic metabolism and gut microbiota, and attempted to relieve the salt-i...

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Detalles Bibliográficos
Autores principales: Ou-Yang, Ya-nan, Yuan, Meng-di, Yang, Zheng-mao, Min, Zhuo, Jin, Yue-xin, Tian, Zhong-min
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694938/
https://www.ncbi.nlm.nih.gov/pubmed/36355159
http://dx.doi.org/10.3390/metabo12111076