Formulation and Optimization of Metronidazole and Lactobacillus spp. Layered Suppositories via a Three-Variable, Five-Level Central Composite Design for the Management of Bacterial Vaginosis

Bacterial vaginosis, a polymicrobial clinical syndrome characterized by a shift in healthy vaginal microbiota due to bacterial colonization, is characterized by high recurrence rates after conventional treatment with an antimicrobial agent. This has necessitated the need to develop a formulation tha...

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Detalles Bibliográficos
Autores principales: Ilomuanya, Margaret O., Salako, Busayo B., Ologunagba, Modupe O., Shonekan, Omonike O., Owodeha-Ashaka, Kruga, Osahon, Eseosa S., Amenaghawon, Andrew N.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694961/
https://www.ncbi.nlm.nih.gov/pubmed/36365154
http://dx.doi.org/10.3390/pharmaceutics14112337

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694961/
https://www.ncbi.nlm.nih.gov/pubmed/36365154
http://dx.doi.org/10.3390/pharmaceutics14112337

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