A Short 5′triphosphate RNA nCoV-L Induces a Broad-Spectrum Antiviral Response by Activating RIG-I

Small molecular nucleic acid drugs produce antiviral effects by activating pattern recognition receptors (PRRs). In this study, a small molecular nucleotide containing 5′triphosphoric acid (5′PPP) and possessing a double-stranded structure was designed and named nCoV-L. nCoV-L was found to specifica...

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Detalles Bibliográficos
Autores principales: Song, Ziyang, Wang, Qian, Bian, Lianlian, An, Chaoqiang, Cui, Bopei, Mao, Qunying, Wu, Xing, He, Qian, Bai, Yu, Liu, Jianyang, Song, Lifang, Liu, Dong, Zhang, Jialu, Gao, Fan, Li, Xiuling, Liang, Zhenglun
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694983/
https://www.ncbi.nlm.nih.gov/pubmed/36366549
http://dx.doi.org/10.3390/v14112451

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694983/
https://www.ncbi.nlm.nih.gov/pubmed/36366549
http://dx.doi.org/10.3390/v14112451

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