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Airway Smooth Muscle Cell Mitochondria Damage and Mitophagy in COPD via ERK1/2 MAPK

Chronic obstructive pulmonary disease (COPD) is characterized by irreversible deterioration of the airway wall. Cigarette smoking is the major trigger, and in vitro studies showed that cigarette smoke extract (CSE) induced mitophagy in airway epithelial cells via oxidative stress, but this mechanism...

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Detalles Bibliográficos
Autores principales: Fang, Lei, Zhang, Ming, Li, Junling, Zhou, Liang, Tamm, Michael, Roth, Michael
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694999/
https://www.ncbi.nlm.nih.gov/pubmed/36430467
http://dx.doi.org/10.3390/ijms232213987