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Airway Smooth Muscle Cell Mitochondria Damage and Mitophagy in COPD via ERK1/2 MAPK
Chronic obstructive pulmonary disease (COPD) is characterized by irreversible deterioration of the airway wall. Cigarette smoking is the major trigger, and in vitro studies showed that cigarette smoke extract (CSE) induced mitophagy in airway epithelial cells via oxidative stress, but this mechanism...
Autores principales: | Fang, Lei, Zhang, Ming, Li, Junling, Zhou, Liang, Tamm, Michael, Roth, Michael |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9694999/ https://www.ncbi.nlm.nih.gov/pubmed/36430467 http://dx.doi.org/10.3390/ijms232213987 |
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