Prevention of bleomycin‐induced lung fibrosis via inhibition of the MRTF/SRF transcription pathway

Bleomycin‐induced lung fibrosis is a debilitating disease, linked to high morbidity and mortality in chemotherapy patients. The MRTF/SRF transcription pathway has been proposed as a potential therapeutic target, as it is critical for myofibroblast differentiation, a hallmark of fibrosis. In human lu...

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Detalles Bibliográficos
Autores principales: Pawelec, Kendell M., Varnum, Megan, Harkema, Jack R., Auerbach, Bruce, Larsen, Scott D., Neubig, Richard R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Original Articles
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695093/
https://www.ncbi.nlm.nih.gov/pubmed/36426895
http://dx.doi.org/10.1002/prp2.1028

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695093/
https://www.ncbi.nlm.nih.gov/pubmed/36426895
http://dx.doi.org/10.1002/prp2.1028

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