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Heat shock protein 40 of Streptococcus pneumoniae induces immune response of human dendritic cells via TLR4‐dependent p38 MAPK and JNK signaling pathways

INTRODUCTION: Heat shock protein 40 (HSP40) is a vaccine adjuvant candidate for Streptococcus pneumoniae. The mechanism by which HSP40 activates the human dendritic cells (DCs) is unclear. METHODS: DCs were isolated from human peripheral blood and their markers (HLA‐DR, CD86, CD83, and CD80) were de...

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Detalles Bibliográficos
Autores principales: Liu, Jing‐jing, Lin, Jian‐cheng, Chen, Li‐na
Formato: Online Artículo Texto
Lenguaje:English
Publicado: John Wiley and Sons Inc. 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695094/
https://www.ncbi.nlm.nih.gov/pubmed/36444618
http://dx.doi.org/10.1002/iid3.735