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Heat shock protein 40 of Streptococcus pneumoniae induces immune response of human dendritic cells via TLR4‐dependent p38 MAPK and JNK signaling pathways
INTRODUCTION: Heat shock protein 40 (HSP40) is a vaccine adjuvant candidate for Streptococcus pneumoniae. The mechanism by which HSP40 activates the human dendritic cells (DCs) is unclear. METHODS: DCs were isolated from human peripheral blood and their markers (HLA‐DR, CD86, CD83, and CD80) were de...
Autores principales: | , , |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
John Wiley and Sons Inc.
2022
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Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695094/ https://www.ncbi.nlm.nih.gov/pubmed/36444618 http://dx.doi.org/10.1002/iid3.735 |