Protrusion of KCNJ13 Gene Knockout Retinal Pigment Epithelium Due to Oxidative Stress–Induced Cell Death

PURPOSE: This study was performed to elucidate the mechanisms of morphological abnormalities in a Leber congenital amaurosis 16 (LCA16) cell model using KCNJ13 knockout (KO) retinal pigment epithelial cells derived from human iPS cells (hiPSC-RPE). METHODS: In KCNJ13 KO and wild-type hiPSC-RPE cells...

Descripción completa

Detalles Bibliográficos
Autores principales: Kanzaki, Yuki, Fujita, Hirofumi, Sato, Keita, Hosokawa, Mio, Matsumae, Hiroshi, Morizane, Yuki, Ohuchi, Hideyo
Formato: Online Artículo Texto
Lenguaje:English
Publicado: The Association for Research in Vision and Ophthalmology 2022
Materias:
Retinal Cell Biology
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695160/
https://www.ncbi.nlm.nih.gov/pubmed/36413373
http://dx.doi.org/10.1167/iovs.63.12.29

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695160/
https://www.ncbi.nlm.nih.gov/pubmed/36413373
http://dx.doi.org/10.1167/iovs.63.12.29

Ejemplares similares