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Bcl-2 Family Members Bcl-xL and Bax Cooperatively Contribute to Bortezomib Resistance in Mantle Cell Lymphoma

Mantle cell lymphoma (MCL) is an aggressive non-Hodgkin lymphoma with poor prognosis, due to the inevitable development of drug resistance. Despite being the first-in-class proteasome inhibitor for relapsed/refractory MCL, resistance to bortezomib (BTZ) in MCL patients remains a major hurdle of effe...

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Detalles Bibliográficos
Autores principales: Luanpitpong, Sudjit, Janan, Montira, Yosudjai, Juthamas, Poohadsuan, Jirarat, Chanvorachote, Pithi, Issaragrisil, Surapol
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695253/
https://www.ncbi.nlm.nih.gov/pubmed/36430955
http://dx.doi.org/10.3390/ijms232214474