Suppression of SREBP-1 Expression by Simvastatin Decreases Visfatin-Induced Chemoresistance to Sunitinib in Human Renal Carcinoma 786-O Cells

The resistance of renal cell carcinoma (RCC) to sunitinib impedes the success of chemotherapy in cancer treatment. Although several sunitinib resistance mechanisms have been proposed, little is known concerning the impact of obesity and adipokines in RCC cells. The upregulation of sterol-regulatory...

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Detalles Bibliográficos
Autores principales: Chen, Te-Chuan, Huang, Chen-Wei, Lo, Chih-Yu, Chen, Cheng-Nan, Chang, Shun-Fu, Chen, Yih-Yuan
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695258/
https://www.ncbi.nlm.nih.gov/pubmed/36431025
http://dx.doi.org/10.3390/life12111890

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695258/
https://www.ncbi.nlm.nih.gov/pubmed/36431025
http://dx.doi.org/10.3390/life12111890

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