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Suppression of SREBP-1 Expression by Simvastatin Decreases Visfatin-Induced Chemoresistance to Sunitinib in Human Renal Carcinoma 786-O Cells
The resistance of renal cell carcinoma (RCC) to sunitinib impedes the success of chemotherapy in cancer treatment. Although several sunitinib resistance mechanisms have been proposed, little is known concerning the impact of obesity and adipokines in RCC cells. The upregulation of sterol-regulatory...
Autores principales: | Chen, Te-Chuan, Huang, Chen-Wei, Lo, Chih-Yu, Chen, Cheng-Nan, Chang, Shun-Fu, Chen, Yih-Yuan |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695258/ https://www.ncbi.nlm.nih.gov/pubmed/36431025 http://dx.doi.org/10.3390/life12111890 |
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