Varespladib in the Treatment of Snakebite Envenoming: Development History and Preclinical Evidence Supporting Advancement to Clinical Trials in Patients Bitten by Venomous Snakes

The availability of effective, reliably accessible, and affordable treatments for snakebite envenoming is a critical and long unmet medical need. Recently, small, synthetic toxin-specific inhibitors with oral bioavailability used in conjunction with antivenom have been identified as having the poten...

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Detalles Bibliográficos
Autores principales: Lewin, Matthew R., Carter, Rebecca W., Matteo, Isabel A., Samuel, Stephen P., Rao, Sunita, Fry, Bryan G., Bickler, Philip E.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695340/
https://www.ncbi.nlm.nih.gov/pubmed/36422958
http://dx.doi.org/10.3390/toxins14110783

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695340/
https://www.ncbi.nlm.nih.gov/pubmed/36422958
http://dx.doi.org/10.3390/toxins14110783

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