Development and Validation of an LC-MS/MS Method for Simultaneous Determination of Short Peptide-Based Drugs in Human Blood Plasma

A novel HPLC-ESI-MS/MS method for simultaneous gonadotropin-releasing hormone (GnRH) analogs and somatostatin analog quantitation was developed and validated. The developed method was successfully applied to pharmacokinetic studies. The sample preparation process included solid-phase extraction (SPE...

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Detalles Bibliográficos
Autores principales: Fisher, Elizaveta N., Melnikov, Evgeny S., Gegeckori, Vladimir, Potoldykova, Natalya V., Enikeev, Dmitry V., Pavlenko, Kirill A., Agatonovic-Kustrin, Snezana, Morton, David W., Ramenskaya, Galina V.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Article
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695356/
https://www.ncbi.nlm.nih.gov/pubmed/36431933
http://dx.doi.org/10.3390/molecules27227831

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695356/
https://www.ncbi.nlm.nih.gov/pubmed/36431933
http://dx.doi.org/10.3390/molecules27227831

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