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Shedding a Light on Acyclovir Pharmacodynamics: A Retrospective Analysis on Pharmacokinetic/Pharmacodynamic Modelling of Acyclovir for the Treatment of Varicella Zoster Virus Infection in Immunocompromised Patients: A Pilot Study

Background: Acyclovir and valacyclovir are used for the treatment and prophylaxis of infections with herpes simplex virus (HSV) and varicella zoster virus (VZV). The aim of this study is to provide insight into the pharmacodynamics (PD) of (val)acyclovir. Methods: Patients were retrospectively selec...

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Detalles Bibliográficos
Autores principales: Grit, Geeske F., Märtson, Anne-Grete, Knoester, Marjolein, Toren-Wielema, Marlous L., Touw, Daan J.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695373/
https://www.ncbi.nlm.nih.gov/pubmed/36365129
http://dx.doi.org/10.3390/pharmaceutics14112311