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Mitochondria-Targeted Human Catalase in the Mouse Longevity MCAT Model Mitigates Head-Tilt Bedrest-Induced Neuro-Inflammation in the Hippocampus

Microgravity (modeled by head-tilt bedrest and hind-limb unloading), experienced during prolonged spaceflight, results in neurological consequences, central nervous system (CNS) dysfunction, and potentially impairment during the performance of critical tasks. Similar pathologies are observed in bedr...

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Detalles Bibliográficos
Autores principales: Rubinstein, Linda, Kiffer, Frederico, Puukila, Stephanie, Lowe, Moniece G., Goo, Brie, Luthens, Amalia, Schreurs, Ann-Sofie, Torres, Samantha M., Steczina, Sonette, Tahimic, Candice G. T., Allen, Antiño R.
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695374/
https://www.ncbi.nlm.nih.gov/pubmed/36362993
http://dx.doi.org/10.3390/life12111838