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Mitochondria-Targeted Human Catalase in the Mouse Longevity MCAT Model Mitigates Head-Tilt Bedrest-Induced Neuro-Inflammation in the Hippocampus
Microgravity (modeled by head-tilt bedrest and hind-limb unloading), experienced during prolonged spaceflight, results in neurological consequences, central nervous system (CNS) dysfunction, and potentially impairment during the performance of critical tasks. Similar pathologies are observed in bedr...
Autores principales: | Rubinstein, Linda, Kiffer, Frederico, Puukila, Stephanie, Lowe, Moniece G., Goo, Brie, Luthens, Amalia, Schreurs, Ann-Sofie, Torres, Samantha M., Steczina, Sonette, Tahimic, Candice G. T., Allen, Antiño R. |
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Formato: | Online Artículo Texto |
Lenguaje: | English |
Publicado: |
MDPI
2022
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Materias: | |
Acceso en línea: | https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695374/ https://www.ncbi.nlm.nih.gov/pubmed/36362993 http://dx.doi.org/10.3390/life12111838 |
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