Targeting the Complement–Sphingolipid System in COVID-19 and Gaucher Diseases: Evidence for a New Treatment Strategy

Severe Acute Respiratory Syndrome Coronavirus-2 (SARS-CoV-2)-induced disease (COVID-19) and Gaucher disease (GD) exhibit upregulation of complement 5a (C5a) and its C5aR1 receptor, and excess synthesis of glycosphingolipids that lead to increased infiltration and activation of innate and adaptive im...

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Detalles Bibliográficos
Autores principales: Trivedi, Vyoma Snehal, Magnusen, Albert Frank, Rani, Reena, Marsili, Luca, Slavotinek, Anne Michele, Prows, Daniel Ray, Hopkin, Robert James, McKay, Mary Ashley, Pandey, Manoj Kumar
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695449/
https://www.ncbi.nlm.nih.gov/pubmed/36430817
http://dx.doi.org/10.3390/ijms232214340

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695449/
https://www.ncbi.nlm.nih.gov/pubmed/36430817
http://dx.doi.org/10.3390/ijms232214340

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