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Flagellin Improves the Immune Response of an Infectious Bursal Disease Virus (IBDV) Subunit Vaccine

Flagellin activates the immune system through Toll-like receptor 5 (TLR5) and can work as an adjuvant for subunit vaccines. In this study, we tested the adjuvancy of two different N-terminal fragments of flagellin, (1) FliC(99), residues 1–99, and (2) FliC(176), residues 1–176, to incorporate larger...

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Detalles Bibliográficos
Autores principales: Murtaza, Asad, Afzal, Haroon, Doan, Thu-Dung, Ke, Guan-Ming, Cheng, Li-Ting
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695526/
https://www.ncbi.nlm.nih.gov/pubmed/36366289
http://dx.doi.org/10.3390/vaccines10111780