Mind the Gap—Deciphering GPCR Pharmacology Using 3D Pharmacophores and Artificial Intelligence

G protein-coupled receptors (GPCRs) are amongst the most pharmaceutically relevant and well-studied protein targets, yet unanswered questions in the field leave significant gaps in our understanding of their nuanced structure and function. Three-dimensional pharmacophore models are powerful computat...

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Detalles Bibliográficos
Autores principales: Noonan, Theresa, Denzinger, Katrin, Talagayev, Valerij, Chen, Yu, Puls, Kristina, Wolf, Clemens Alexander, Liu, Sijie, Nguyen, Trung Ngoc, Wolber, Gerhard
Formato: Online Artículo Texto
Lenguaje:English
Publicado: MDPI 2022
Materias:
Review
Acceso en línea:https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695541/
https://www.ncbi.nlm.nih.gov/pubmed/36355476
http://dx.doi.org/10.3390/ph15111304

Internet

https://www.ncbi.nlm.nih.gov/pmc/articles/PMC9695541/
https://www.ncbi.nlm.nih.gov/pubmed/36355476
http://dx.doi.org/10.3390/ph15111304

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